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王祎

发布时间:2020-07-10      作者:学科办      审核:      编辑:吴靓      点击:
审核人

姓名:王祎

职称:副教授

简历:

2007年毕业于四川大学华西基础医学与法医学院,获基础医学学士学位。

2014年毕业于美国德克萨斯大学西南医学中心(University of Texas Southwestern Medical Center at Dallas),获生物化学博士学位并进行博士后研究工作。

2015年入职四川大学华西基础医学与法医学院病理生理教研室。

2017/08-2018/07,2019/08-2020/02两次获邀赴美国马萨诸塞大学医学院(University of Massachusetts Medical school)基因治疗中心进行访问研究。

入职四川大学以来,从事病理生理学教学和研究工作,参编普通高等教育“十三五”规划教材《病理生理学》,获四川省科技进步二等奖,四川省卫健委学术技术带头人后备等荣誉。以第一作者或共同通讯作者在 Nucleic Acids Res,Cell Death Dis,Free Radic Biol Med,Sci Rep 等国际知名学术期刊上发表论文数篇。先后承担国家自然科学基金青年科学基金项目,地区项目。

 

研究方向:1.天然免疫的表观遗传调控机制研究

2.肝脏疾病的基因治疗研究

 

联系方式:电子邮箱:wy4504228@163.com

电话:15881110964

 

学术荣誉:

2015年四川省科技进步二等奖

2019年四川省卫健委学术技术带头人后备

2020年第二十三届美国基因与细胞治疗协会年会Travel award

学术任职:

美国基因与细胞治疗协会会员

中国病理生理学会会员

SCI期刊 Human gene therapy 杂志特邀审稿人

中文核心期刊《心血管病学进展》编委

会议报告:

第二十三届美国基因与细胞治疗协会年会(2020/05)

23rd Annual Meeting of the American Society of Gene & Cell Therapy

报告题目:

“rAAV-Mediated Hepatocyte-Specific Expression of miR-375 Protects Against the Acetaminophen-Induced Acute Liver Failure in Mice”

发表论文:

2020

  1. Feimei Zhu, Feng Xiong, Jinchen He, Keyun Liu, Yuanyuan You, Qian Xu, Junming Miao, Yu Du, Lijuan Zhang, Hongyu Ren, Xiaoying Wang, Junli Chen, Jingyu Li, Shanze Chen, Xiaokang Liu, Ning Huang*,Yi Wang*.Brd4 inhibition ameliorates Pyocyanin-mediated macrophage dysfunction via transcriptional repression of reactive oxygen and nitrogen free radical pathways.Cell Death Dis. 2020 Jun; 11(6): 459. Published online 2020 Jun 15. doi: 10.1038/s41419-020-2672-0(影响因子5.9共同通讯)

  2. Julia V DiFiore,Travis S Ptacek,Yi Wang,Bing Li,Jeremy M Simon,Brian D Strahl. Unique and Shared Roles for Histone H3K36 Methylation States in Transcription Regulation Functions.Cell Rep 2020 Jun 9;31(10):107751.doi: 10.1016/j.celrep.2020.107751.(影响因子7.8)

2019

  1. Xie J,Tai PWL,Brown A,Gong S,Zhu S,Wang Y,Li C,Colpan C,Su Q,He R,Ma H,Li J,Ye H,Ko J,Zamore PD,Gao G. Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold.Mol Ther.2019 Nov 27. pii: S1525-0016(19)30536-2.(影响因子8.4)

  2. You Y, Chen J, Zhu F, Xu Q, Han L, Gao X, Zhang X, Luo HR, Miao J, Sun X, Ren H, Du Y, Guo L, Wang X,Wang Y, Chen S, Huang N, Li J,Glutaredoxin 1 up-regulates deglutathionylation of α4 integrin and thereby restricts neutrophil mobilization from bone marrow.J Biol Chem. 2019 Feb 22;294(8):2616-2627. doi: 10.1074/jbc.RA118.006096. Epub 2018 Dec 31.(影响因子4.1)

2018

  1. Tian H, Miao J, Zhang F, Xiong F, Zhu F, Li J, Wang X, Chen S, Chen J, Huang N*,Wang Y*,Non-histone nuclear protein HMGN2 differently regulates the urothelium barrier function by altering expression of antimicrobial peptides and tight junction protein genes in UPEC J96-infected bladder epithelial cell monolayer.Acta Biochim Pol.2018;65(1):93-100. doi: 10.18388/abp.2017_1622. Epub 2018 Mar 17.(影响因子1.6,共同通讯)

    2017

  2. Liu, K., Wang. X, Sha. K, Zhang. F, Xiong. F, Wang. X, Chen. J, Li. J, Chen. S, Huang. N*, Wang. Y*, Nuclear protein HMGN2 attenuates PCN-induced oxidative stress via Nrf2 signaling and inhibits Pseudomonas aeruginosa internalization in A549 cells.Free Radic Biol Med. 2017 Apr 10;108:404-417. doi: 10.1016/j.freeradbiomed.2017.04.007.(影响因子5.7,共同通讯)

    2016

  3. Teng, Y., Miao. J, Shen. X, Yang. X, Wang. X, Ren. L, Wang. X, Chen. J, Li. J, Chen. S,Wang. Y*, Huang. N*, The modulation of MiR-155 and MiR-23a manipulatesKlebsiella pneumoniaeAdhesion on Human pulmonary Epithelial cells via Integrin α5β1 Signaling.Sci Rep 2016 Aug 18;6:31918. doi: 10.1038/srep31918.(影响因子4.0,共同通讯)

  4. Zheng,S. Gao,X. Liu,X. Yu,T. Zheng,T.Wang,Y. You,C, Biodegradable micelles enhance the anti-glioma activity of curcumin in vitro and in vivo.Int J Nanomedicine, 2016. 2016:11 P.2721—2736(影响因子4.4)

    2015

    1. Wang, Y., Y. Niu, and B. Li, Balancing acts of SRI and an auto-inhibitory domain specify Set2 function at transcribed chromatin.Nucleic Acids Res, 2015. 43(10): p. 4881-92. (影响因子11.1,第一作者)

    2009

    1. Deng, L.,Pan. X,Wang. Y, Wang. L, Zhou. XE, Li. M, Feng. Y, Wu. Q, Wang. B, Huang. N. Hemoglobin and its derived peptides may play a role in the antibacterial mechanism of the vagina.Hum Reprod, 2009. 24(1): p. 211-8.(影响因子5.5)

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