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郑 煜

发布时间:2016-06-03      作者:学院办公室      审核:      编辑:      点击:
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    郑 煜,博士,教授,博导。1977年毕业于四川医学院,1985年获华西医科大学生理学硕士学位,1990年获法国艾克斯·马赛第三大学神经科学博士学位。历任四川医学院/华西医科大学/四川大学生理学助教(1977-)、讲师(1986-)、副教授(1992-)、教授(1997-)、博导(1998-),生理学教研室主任(1994-2001),华西基础医学与法医学院副院长(2001-2011),中国生理学会常务理事(1998-2010)、教学工作委员会副主任委员(1998-2002)、继续教育工作委员会主任委员(2002-2010)、呼吸生理学专业委员会副主任委员(2006-2014),四川省生理科学会副理事长、生理学专业委员会主任委员(2006-2015),四川生理科学杂志副主编、生理学报、生物医学工程学杂志、四川大学学报(医学版)等杂志常务编委或编委。

    一直从事本科生和研究生教育教学工作,承担国家级和部省级教改项目4项,发表教学研究论文/论文摘要近20篇,获省级教学成果奖2项,主编教材4部、副主编2部、参编10余部,培养硕士研究生30余名、博士研究生20余名。

    长期从事呼吸神经生物学研究工作,曾在法国国家科学研究中心Fessard研究所、美国Rockefeller大学、香港大学、法国艾克斯·马赛第三大学研修或合作科研,先后主持国家自然科学基金项目7项和部省级基金项目6项,发表学术论文110余篇(其中SCI收录40余篇),获国家发明专利和实用新型专利各1项,部省级科技成果奖3项。

    获四川省突贡专家(1998)、国务院政府特殊津贴获得者(2001)、四川省学术带头人(2006)、四川省教学名师(2008)、宝钢优秀教师(2014)等荣誉或奖励。

    科研方向:呼吸神经生物学(呼吸调节与调节障碍)

    近年来代表性学术论文(通讯作者):

    1Senfeng Zhang,Fang Lei,Fusheng Zhao, Xiang Yan, Wen Wang, Yu Zheng.Hydrogen sulfide ameliorates prenatal cigarette smoke exposure-inducedimpairment of respiratory responses to hypercapnia in neonatal rats.Respiratory Physiology & Neurobiology 243:1-6, 2017.

    2Fusheng Zhao, Fang Lei, Senfeng Zhang, Xiang Yan, Wen Wang, Yu Zheng.Hydrogen sulfide alleviates placental injury induced by maternalcigarette smoke exposure during pregnancy in rats.Nitric Oxide xxx (2017) 1-10.doi: 10.1016/j.niox.2017.07.003. [Epub ahead of print]

    3Yan Ding, Xuefei Hou, Li Chen, Hua Zhou, Yanju Gong, Liqun Dai, Yu Zheng. Heme oxygenase-1 dependant pathway contributes to protection by tetramethylpyrazine against chronic hypoxic injury on medulla oblongata in rats. Journal of Neurological Sciences 361:101-111, 2016.

    4Hui Li,Li Chen,Xuefei Hou,Hua Zhou,Yu Zheng.Hydrogen sulfide attenuates hypoxia-induced respiratory suppressionin anesthetized adult rats. Respiratory Physiology & Neurobiology 220:1-9, 2016.

    5Fang Lei, Xiang Yan, Fusheng Zhao, Senfeng Zhang, Qilan Zhang, Hua Zhou, Yu Zheng. Impairment ofcentralchemoreception inneonatalratsinduced bymaternalcigarettesmokeexposure duringpregnancy. PLoS ONE 10(9):e0137362,2015.doi:10.1371/journal.pone.0137362.

    6Hui Li, Xuefei Hou, Yan Ding, Lihong Nie, Hua Zhou, Zheng Nie, Yuhong Tang, Li Chen and Yu Zheng. Effects of H2S on the central regulation of respiration in adult rats. NeuroReport 25:358-366, 2014.

    7Li Chen, Jie Zhang, Yan Ding, Hui Li, Lihong Nie, Hua Zhou, Yuhong Tang, Yu Zheng. Site-specific hydrogen sulfide-mediated central regulation of respiratory rhythm in medullary slices of neonatal rats. Neuroscience 233:118-126, 2013.

    8Lihong Nie, Yajie Hu, Xiang Yan, Mingqiang Li, Li Chen, Hui Li, Xianke Li, Hua Zhou, Yu Zheng. The anti-apoptotic effect of hydrogen sulfide attenuates injuries to the medullary respiratory centers of neonatal rats subjected to in utero cigarette smoke exposure. Respiratory Physiology & Neurobiology 188:29-38, 2013.

    9Li Chen, Jie Zhang, Yan Ding, Hui Li, Lihong Nie, Xiang Yan, Hua Zhou. Yu Zheng. KATP channels of parafacial respiratory group (pFRG) neurons are involved in H2S-mediated central inhibition of respiratory rhythm in medullary slices of neonatal rats. Brain Research 1527:141-148, 2013.

    10Mingqiang Li, Lihong Nie, Yajie Hu, Xiang Yan, Lian Xue, Li Chen, Hua Zhou, Yu Zheng. Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata. Autonomic Neuroscience 179:84-89, 2013.

    11Yan Ding, Xuefei Hou, Li Chen, Hui Li, Yuhong Tang, Hua Zhou, Shu Zhao, Yu Zheng. Protective action oftetramethylpyrazine on medulla oblongata in rats with chronic hypoxia. Autonomic Neuroscience 173:45-52, 2013.

    12Li Chen, Jie Zhang, Ying He, Jigang Pan, Hua Zhou, Hui Li, Yuhong Tang, Yu Zheng. Contribution of BKCa channels of neurons in rostral ventrolateral medulla to CO-mediated central regulation of respiratory rhythm in medullary slices of neonatal rats. Respiratory Physiology & Neurobiology 182:93-99, 2012.

    13Jigang Pan, Jie Zhang, Hua Zhou, Li Chen, Yuhong Tang, Yu Zheng. Protective action of endogenously generated H2S on hypoxia-induced respiratory suppression and its relation to antioxidation and down-regulation of c-fos mRNA in medullary slices of neonatal rats. Respiratory Physiology & Neurobiology 178:230-234, 2011.

    14Jie Zhang, Ying He, Yan Ding, Hua Zhou, Yuhong Tang, Li Chen, Yu Zheng. Nitric oxide synthase expression in the medullary respiratory related nuclei and its involvement in CO-mediated central respiratory effects in neonatal rats. Brain Research Bulletin 84:258-263, 2011.

    15Jigang Pan, Haiyan Hu, Jie Zhang, Hua Zhou, Li Chen, Yuhong Tang, Yu Zheng. Protective effect of hydrogen sulfide on hypoxic respiratory suppression in medullary slice of neonatal rats. Respiratory Physiology & Neurobiology 171:181-186, 2010.

    主编教材:

    陈霞,郑煜主编《呼吸系统学习指导及习题集》,人民卫生出版社,2016.

    郑煜,陈霞主编《呼吸系统》,人民卫生出版社,2015.

    郑煜主编《生理学》,高等教育出版社,2010.

    郑煜主编《生理学》,四川大学出版社,2005.

    副主编教材:

    王庭槐主编《生理学》(八年制),第3版,人民卫生出版社,2015.

    朱大年,王庭槐主编《生理学数字教材》,人民卫生出版社,2015.

    主要参编教材:

    朱大年,王庭槐主编《生理学》(五年制),第8版,人民卫生出版社,2013.

    姚泰主编《生理学》(八年制),第2版,人民卫生出版社,2010.

    姚 泰主编《Textbook of Physiology》,人民卫生出版社,2008.

    朱大年主编《生理学》(五年制),第7版,人民卫生出版社,2008.

    姚 泰主编《生理学》(八年制),第1版,人民卫生出版社,2005.

    姚泰主编《生理学》(五年制),第6版,人民卫生出版社,2003.

    姚泰主编《生理学》(五年制),第5版,人民卫生出版社,2000.

    张镜如主编《生理学》(五年制),第4版,人民卫生出版社,1996.

    参编参考书:

    唐朝枢主编《中华医学百科全书》人体生理学分卷,中国协和医科大学出版社,2017.

    姚泰,赵志奇,朱大年,杨雄里主编《人体生理学》,第4版,人民卫生出版社,2015.

     

    ZHENG YU, Ph.D

    Professor

    Department of Physiology

    West China School of Basic Medical Sciences & Forensic Medicine

    Sichuan University

    Address:

    No.17 the 3rd section of South People Road, Chengdu, Sichuan Province

    Phone Number: 86-28-85502389

    Email Address: yzheng@scu.edu.cn

    Graduated from Sichuan Medical College in 1977, obtained master degree from West China University of Medical Sciences in 1985 and doctoral degree from Universite Aix-Marseille III, France in 1990.

    Professor of Physiology (1997- ), head of Department of Physiology (1994-2001), and vice dean of West China School of Basic Medical Sciences and Forensic Medicine (2001-2011) in Sichuan University, executive member of the council of Chinese Association of Physiological Sciences (1998-2010), chairman of Physiological Society of Sichuan Province (2006-2015), member of editorial board of Acta Physiologica Sinica, Journal of Biomedical Engineering, Journal of Sichuan University (Medical Science Edition) and some others.

    The major research interest has been focused on neurobiology, especially the neural control of breathing and respiration-related activities. The main works we previously did include the effects of stimulating acupoint “Renzhong” on respiration and the underlying mechanism in rabbits, the electrophysiological and morphological properties of the respiratory neurons in medulla oblongata in rats, the roles of the medullary respiratory neurons in regulation of respiration and respiration-related activities in cats, and the effects of ischemia or hypoxia of brainstem on respiration and the protective strategies in rats. The recent main work focuses on the biological actions of H2S in rats.

     

    RECENT MAIN PUBLICATIONS (AS CORRESPONDING AUTHOR):

    Fusheng Zhao, Fang Lei, Senfeng Zhang, Xiang Yan, Wen Wang, Yu Zheng. Hydrogen sulfide alleviates placental injury induced by maternal cigarette smoke exposure during pregnancy in rats. Nitric Oxide xxx (2017) 1-10. doi: 10.1016/j.niox.2017.07.003. [Epub ahead of print]

    Senfeng Zhang, Fang Lei, Fusheng Zhao, Xiang Yan, Wen Wang, Yu Zheng. Hydrogen sulfide ameliorates prenatal cigarette smoke exposure-induced impairment of respiratory responses to hypercapnia in neonatal rats. Respiratory Physiology & Neurobiology 243:1-6, 2017.

    Yan Ding, Xuefei Hou, Li Chen, Hua Zhou, Yanju Gong, Liqun Dai, Yu Zheng. Heme oxygenase-1 dependant pathway contributes to protection by tetramethylpyrazine against chronic hypoxic injury on medulla oblongata in rats. Journal of Neurological Sciences 361:101-111, 2016.

    Hui Li, Li Chen, Xuefei Hou, Hua Zhou, Yu Zheng. Hydrogen sulfide attenuates hypoxia-induced respiratory suppression in anesthetized adult rats. Respiratory Physiology & Neurobiology 220:1-9, 2016.

    Fang Lei, Xiang Yan, Fusheng Zhao, Senfeng Zhang, Qilan Zhang, Hua Zhou, Yu Zheng. Impairment of central chemoreception in neonatal rats induced by maternal cigarette smoke exposure during pregnancy. PLoS ONE 10:e0137362, 2015. doi: 10.1371/journal.pone.0137362.

    Hui Li, Xuefei Hou, Yan Ding, Lihong Nie, Hua Zhou, Zheng Nie, Yuhong Tang, Li Chen and Yu Zheng. Effects of H2S on the central regulation of respiration in adult rats. NeuroReport 25:358-366, 2014.

    Li Chen, Jie Zhang, Yan Ding, Hui Li, Lihong Nie, Hua Zhou, Yuhong Tang, Yu Zheng. Site-specific hydrogen sulfide-mediated central regulation of respiratory rhythm in medullary slices of neonatal rats. Neuroscience 233:118-126, 2013.

    Lihong Nie, Yajie Hu, Xiang Yan, Mingqiang Li, Li Chen, Hui Li, Xianke Li, Hua Zhou, Yu Zheng. The anti-apoptotic effect of hydrogen sulfide attenuates injuries to the medullary respiratory centers of neonatal rats subjected to in utero cigarette smoke exposure. Respiratory Physiology & Neurobiology 188:29-38, 2013.

    Li Chen, Jie Zhang, Yan Ding, Hui Li, Lihong Nie, Xiang Yan, Hua Zhou. Yu Zheng. KATP channels of parafacial respiratory group (pFRG) neurons are involved in H2S-mediated central inhibition of respiratory rhythm in medullary slices of neonatal rats. Brain Research 1527:141-148, 2013.

    Mingqiang Li, Lihong Nie, Yajie Hu, Xiang Yan, Lian Xue, Li Chen, Hua Zhou, Yu Zheng. Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata. Autonomic Neuroscience 179:84-89, 2013.

    Yan Ding, Xuefei Hou, Li Chen, Hui Li, Yuhong Tang, Hua Zhou, Shu Zhao, Yu Zheng. Protective action of tetramethylpyrazine on medulla oblongata in rats with chronic hypoxia. Autonomic Neuroscience 173:45-52, 2013.

    TEXTBOOK EDITOR-IN-CHIEF:

    Direction of Learning and Problem Sets of Respiratory System, The Peoples Medical Publishing House, 2016.

    Textbook of Respiratory System, The Peoples Medical Publishing House, 2015.

    Textbook of Physiology, The Higher Education Press, 2010.

    Textbook of Physiology, The Sichuan University Press, 2005.

    TEXTBOOK ASSOCIATE EDITOR-IN-CHIEF:

    Textbook of Physiology, (8 Year Educational System), 3rd Ed, The Peoples Medical Publishing House, 2015.

    Digital Textbook of Physiology, The Peoples Medical Publishing House, 2015.

    TEXTBOOK EDITOR:

    Textbook of Physiology, 8th Ed, The Peoples Medical Publishing House, 2013.

    Textbook of Physiology, (8 Year Educational System), 2nd Ed, The Peoples Medical Publishing House, 2010.

    Textbook of Physiology, 7th Ed, The Peoples Medical Publishing House, 2008.

    Textbook of Physiology, (8 Year Educational System), 1st Ed, The Peoples Medical Publishing House, 2005.

    Textbook of Physiology, 6th Ed, The Peoples Medical Publishing House, 2003.

    Textbook of Physiology, 5th Ed, The Peoples Medical Publishing House, 2000.

    Textbook of Physiology, 4th Ed, The Peoples Medical Publishing House, 1996.

    BOOK CHAPTER EDITOR:

    Medical Encyclopedia of China: Sub-volume of Human Physiology, China union medical university press, 2017.

    Human Physiology, 4th Ed, The Peoples Medical Publishing House, 2015.

     

     

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